A research paper has shed new light on the complex process causing progression of Alzheimer’s disease (AD) in the human brain. Signs of increased inflammation are linked to disturbance of the normal processes of cell protection and recovery.

The final recovery phase of inflammation is a cellular step, the process of resolution, which is facilitated by specific mediators derived from fatty acids. If this does not occur, the inflammation process is never terminated and advances unchecked, as in Alzheimer’s disease. The research has found that one important mediator, Lipoxin (LXA4), is significantly reduced in those suffering from this disease. Finding a method of elevating LXA4 may provide a route to controlling the advance of AD.

The link to the article is: http://www.alzheimersanddementia.com/article/S1552-5260(14)00030-2