Over the past few years the hype about ketones has increased, but why?
In the late 1990’s researchers discovered the impairment of glucose metabolism in Alzheimer’s patients1. Impairment in glucose metabolism reduces the energy available to the brain and, therefore, reduces function.
As research has progressed, the previous findings led to a method capable of determining the severity of the disease by monitored the decline of glucose metabolism2. This made the hypo metabolism of glucose a therapeutic target for Alzheimer’s disease.
This is all well and good but how do we build on this?
It was found that when people fast or starve, their fat reserves are converted into natural ketones which can then be used as energy. However, the brain cannot efficiently convert fats to ketones which results in energy starvation. Administered ketones have been found to efficiently supplement glucose supplies to the brain3.
So, if the ketones are provided directly, the brain can use them as an alternative energy source, quenching the starvation and returning the brain to normal function.
This form of therapy can be vitally important in the early stages of dementia.
KetoactiveEnergy provides an MCT shot when you’re on the move, or need a quick boost which your body can convert into Ketone bodies.
1 Impairment of Neocortical Metabolism Predicts Progression in Alzheimer’s Disease. K. Herholz, A. Nordberg, E. Salmon, D. Perani, J. Kessler, R. Mielke, M. Halber, V. Jelic, O. Almkvist, F. Collette, M. Alberoni, A. Kennedy, s. Hasselbalch, F. Fazio, D. Heiss. Dement Geriatr Cogn Disord 10 (1999) 494–504
2 Early detection of Alzheimer’s disease using neuroimaging. L. Mosconi, M. Brys, L. Glodzik-Sobanska, S. De Santi, H. Rusinek, M. J. de Leon. Experimental Gerontology 42 (2007) 129–138
3 Ketone Bodies as a Therapeutic for Alzheimer’s Disease. S T. Henderson. Neurotherapeutics: The Journal of the American Society for Experimental NeuroTherapeutics 5 (2008) 470 – 480