β-hydroxybutyrate exerts anti-aging effects in vascular cells

An article published in Molecular Cell Sept 2018 has shown that β-hydroxybutyrate (β-hb) exerts anti-aging effects in vascular cells by upregulating an hnRNP A1-induced Oct4-mediated Lamin B1 pathway.

It is well know that β-hb has a positive effect on brain tissue, but less is known about wider health benefits.

In this research the β-hb was made by the body itself through calorie restriction and direct injection of β-hb. The figure below shows the mechanism of action, where reduced senescence is reduced ageing.

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If you would like to read more of the article follow the link to https://goo.gl/4pyhPD

 

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